News Archive - Mario Aguilera

Trained Viruses Prove More Effective at Fighting Antibiotic Resistance

Research reveals that phage viruses that undergo special evolutionary training increase their capacity to subdue bacteria. The results provide hope for the antibiotic resistance crisis, a rising threat as deadly bacteria continue to evolve to render many modern drugs ineffective.

Synthetic SPECIES Developed for Use as a Confinable Gene Drive

Scientists have developed a gene drive with a built-in genetic barrier that is designed to keep the drive under control. The researchers engineered synthetic fly species that, upon release in sufficient numbers, act as gene drives that can spread locally and be reversed if desired.

Researchers Create New CRISPR Tools to Help Contain Mosquito Disease Transmission

Scientists have developed a toolkit that helps pave the way to a gene drive designed to stop Culex mosquitoes from spreading disease. Culex mosquitoes spread devastating afflictions stemming from West Nile virus, Japanese encephalitis virus and the pathogen causing avian malaria.

Research Uncovers How ‘Non-professional’ Cells Can Trigger Immune Response

Researchers are finding new details on the complex dynamics involved in how organisms sense an infection from pathogens. The researchers found that worms can sense changes in their metabolism in order to unleash protective defenses, even if they don’t directly sense an incursion from pathogens.

Plant Consumers Play Unexpectedly Large Role in the Evolution of Seedling Success

Scientists have found that herbivores have a lot to say about plant evolution and determining the success of seedlings. The influence of birds, rabbits, mice and other herbivores likely counteracts early plant emergence due to climate change, the researchers found.

New Genetic ‘CopyCatchers’ Detect Efficient and Precise CRISPR Editing in a Living Organism

Scientists have developed a novel CRISPR-based genetic sensor called a “CopyCatcher” to detect instances in which a genetic element is copied precisely from one chromosome to another in cells of a fruit fly.

New View of Species Interactions Offers Clues to Preserve Threatened Ecosystems

Scientists from around the world have produced a new analysis—believed to be the most detailed study of ecological data from global forests—that is furthering science’s understanding of species interactions and how diversity contributes to the preservation of ecosystem health.

Breakthrough with Quantum Materials Pushes Biologically Inspired Learning Devices

UC San Diego physicists have created new artificial devices that mimic basic learning functions carried out by neurons in the human brain. They demonstrated how quantum materials could be used to develop new devices that can “learn” to switch between functional states.

New Blueprint of Brain Connections Reveals Extensive Reach of Central Regulator

UC San Diego researchers have generated a new map of brain connectivity from a part of the brain called the basal ganglia, a hub for regulating motor and behavior functions. The breadth of connections revealed could potentially open avenues for intervention of Parkinson’s disease and other disorders

Distinct Parkinson’s Disease Symptoms Tied to Different Brain Pathways

Neurobiologists have found that identifiable brain pathways are linked with specific debilitating symptoms of Parkinson’s disease. The findings could help form the basis for improving therapeutic strategies for precise symptoms of Parkinson’s at various levels of disease progression.